Ingredient information: Glucosamine
What is glucosamine?
Glucosamine is a derivative of glucose, which participates in the glycosylation of proteins and lipids.
It is a normal component of the polysaccharide chain of the cartilage matrix and of the glycosaminoglycans of the synovial fluid.
Studies In vitro and in vivo studies have shown that glucosamine stimulates the synthesis of:
- proteoglycans
- glycosaminoglycans by chondrocytes
- hyaluronic acid by the synoviocytes
It is therefore one of the components of cartilage with some effectiveness in supplementation, it is regularly used in the treatment of rheumatism, particularly that which affects the knees.
What are the properties of glucosamine?
Its action is thought to occur via the synovial fluid . Clinical studies are not always clear regarding its effectiveness; however, glucosamine is used as a medication in several countries.
It is available for sale without a prescription in France, but its use requires some precautions.
What are the health claims of glucosamine?
EFSA has not validated the claims of glucosamine (relating to inflammation, immune system, cartilage destruction and joint mobility) concerning food supplements (but not for medicines).
Glucosamine at Phytocea
At Phytocea , for its effects in stimulating cartilage components, we have chosen to include glucosamine in the Kinesis formula.
Kinesis is a nutraceutical food supplement for painful or stressed joints, designed to improve joint comfort and mobility.
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What are the contraindications and side effects of glucosamine?
Some adverse side effects have been reported to the nutrivigilance system, including:
- thrombocytopenic purpura
- digestive problems
- abdominal pain
- hepatitis
- skin rash and itching
Taking glucosamine, particularly in high doses , can cause nausea, diarrhea, heartburn, stomach pain, redness and itching, hepatitis or purpura.
Precautions should be taken by certain individuals, and medical advice is recommended:
People with diabetes or prediabetes (obesity)
- people with asthma or a food allergy to shellfish or insects
- People with hemophilia or those receiving anticoagulant (anti-vitamin K) treatment
In short, it is recommended not to exceed 1g per day of glucosamine sulfate and to respect the recommended doses.
